Heinrich Schulz (1835-1873) joined Engelhard Steinweg's prestigious piano manufactory in Seesen in the Harz Mountains and continued the business with other employees after the Steinweg family left to found Steinway & Sons in New York in the mid-19th century. His sons, the businessman Franz and the piano maker Albert (1864-1931), founded the "Piano- und Musikhaus Gebr. Schulz" in Mainz in 1888. Franz ran the business while Albert Schulz constantly worked on improving the sound quality of the instruments at the Ibach piano factory in Barmen. The business policy of offering an inexpensive, yet robust and sonorous instrument with a house brand made the Schulz Bros. brand known beyond the region's borders. The idea of providing rental pianos proved to be a second important mainstay. Like his father, Günter Schulz (1907-1978), Albert's son, learned piano making at Ibach in Barmen and completed a commercial apprenticeship. In 1937, he married the piano teacher Johanna Fey (1911-2000), daughter of the Wiesbaden master upholsterer Wilhelm Fey.

During the Second World War, bombs destroyed the store on Neubrunnenplatz in Mainz and the family home on Grosse Bleiche. After the end of the war, Günter Schulz began refurbishing damaged instruments in Wilhelm Fey's upholstery workshop on Zietenring, where there was also a small store. In 1962, Günter Schulz acquired the house at Mühlgasse 11-13 with his son Herward and his wife Erika, where there was sufficient exhibition space and room for a workshop on three floors.

Since 2003, master piano maker Christoph Schulz has been running the business together with his wife, pianist Sabine Schulz-Lediger. The company's own collection of old keyboard instruments from three centuries documents the development of piano making and includes rarities such as a piano with a keyboard arranged in a semicircle and an Art Nouveau grand piano decorated with mother-of-pearl and silver.